Category: Startups

Meet the Entrepreneur

Meet the Entrepreneur: Amanda Allen Discusses emocha, Baltimore and…

Meet the Entrepreneur: Amanda Allen Discusses emocha, Baltimore and FastForward

Emocha Mobile Health was one of the first tenants at FastForward East when it opened in 2015. Two years later, it became one of the first startups to move into Johns Hopkins Technology Ventures’ newest innovation hub, FastForward 1812.

As a FastForward tenant, emocha has added clients from Baltimore to Australia for its mobile health platform that connects patients to health care providers and helps solve problems such as medication adherence, linkage to care and patient engagement.

It played a key role in the Maryland Department of Health and Mental Hygiene’s monitoring of Ebola during the outbreak in 2015. This past August, emocha secured contracts for its medication adherence mobile application from three California counties that have some of the highest rates of latent tuberculosis in the country. They’re now using the same technology for hepatitis C and opioid addiction therapy.

Below, Amanda Allen, emocha’s design lead, discusses the startup’s mission, recent successes, support from FastForward and the strengths of Baltimore (which includes delicious pizza).

In five words, what does your company do?

Mobile health for public health.

If I had a few more words I’d say:

“We help public health resources go further. Using technology that strengthens patient-provider relationships, we reduce costs and improve health outcomes.”

What’s one success that emocha has had that you’re particularly proud of?

We started working with Puerto Rico’s Tuberculosis Control Program a few months ago, and their feedback has been extremely positive. I hung up a direct quote in our office: “This has been a god send and has changed the way we operate. You guys are at the forefront of how technology improves health care.”

For context, health departments have a mandate to watch patients take every dose of their TB medication. Every day, for a six- to nine-month period, health officials drive to patients, or ask patients to come into the clinic. This is called Directly Observed Therapy (DOT). While this method is highly effective, it’s extremely burdensome and expensive to scale.

Emocha offers a digital solution. A mobile app allows a patient to video themselves taking their medication at their convenience. Health care workers then log into emocha on their desktop and review videos at their convenience, dramatically reducing the time and money that is poured into observing each patient in-person. This solution is a big deal for Puerto Rico because 30 to 50 percent of their active TB population is unable to access care and dies each year. This situation is compounded by Puerto Rico’s debt, which is currently over $70 billion.

What are emocha’s goals, and how do you plan to reach them?

Each product has a specific goal (increase medication adherence, monitor an outbreak, link more patients to care in less time), but at a high level, we aim to create technology that solves real problems in public health. We do this through a hybrid of research, design and engineering.

I think one of the reasons we’re successful is because we hold the user experience paramount. As design lead, I try to make sure every interface is easy to understand and enjoyable to use, regardless of a user’s age, location and technical savvy. We do this by engaging patients, healthcare workers and providers early on in the design process. One-on-one interviews, focus groups, direct observation and other interactive design exercises ensure we’re solving the right problem in the right way.

In terms of startups and innovation, what’s one thing that separates Baltimore from other tech hotbeds?

Baltimore is a mid-sized city that offers a diverse range of neighborhoods and people. I rarely want to leave, but when I do, I like having access to larger nearby cities. On top of this, cost of living is fairly inexpensive. Baltimore is a hidden gem, my only fear is that word gets out.

What has been the best part about the FastForward 1812 innovation hub so far?

Every product we develop has a clinical champion that guides our understanding of the problem we’re trying to solve. FastForward’s location within the medical campus allows us to meet more often with the world-renowned experts we work with in HIV, Hepatitis C and Tuberculosis.

I also enjoy the physical co-working space. I usually start my day in our office, but work in huddle spaces and phone booths the rest of the day for a change of scenery.

How has FastForward/Johns Hopkins Technology Ventures helped emocha grow?

Emocha was invented by clinicians and researchers at Johns Hopkins in 2008, and Johns Hopkins Technology Ventures helped us license the technology in 2013. They also provided access to the DreamIT Health Accelerator which was instrumental to our start.

Since then, they’ve continued to make introductions to customers and thought leaders in healthcare.

What book are you currently reading?

The Emperor of All Maladies: A Biography of Cancer” by Siddhartha Mukherjee

What innovator do you look up to? Why?

I think I’m most impressed by social entrepreneurs getting by through sheer will power, hustle. They’re usually determined to solve a problem their deeply connected to.

I’ve met two recently who are a part of FastForward’s Social Innovation Lab. Brittany Young is providing a pipeline from dirt biking to STEM jobs through her nonprofit B360, and Shantell Roberts is working to eliminate SIDS by providing an innovative safe sleep solution called a Portable Alternative Cribs (P.A.C.s). Watch out for them.

It’s after a long day of work, and you don’t feel like cooking. What is your go-to Baltimore restaurant?

Lebanese Taverna. But if I’m extra lazy, I order chicken tiki marsala pizza from Charles Restaurant and Carry Out. Look it up. You’re welcome.

What’s your favorite non-work-related thing to do in Baltimore?

I joke that hobbies are for people who don’t like their jobs. But I do enjoy Baltimore’s vibrant bar scene. I like to bring everyone I love together at brunch as often as possible.

Want to learn more about FastForward 1812? Click here.

 

Startups

Acute Kidney Injury: A Startup’s Solution for This Silent…

Acute Kidney Injury: A Startup’s Solution for This Silent Killer

 

A disturbing fact stuck with Aaron Chang throughout his rotation in cardiac surgery. On average, 15 percent of cardiac surgeries result in acute kidney injury (AKI), a condition which greatly impacts life expectancy. Even more disturbing, patients who sustain a stage 1 kidney injury, the least severe of the three stages before kidney failure, become 2.2 times more likely to die within five years.

“Acute kidney injury is the silent killer nobody talks about,” says Chang, a 2015 master’s graduate of the Johns Hopkins School of Biomedical Engineering.

In addition to their serious health detriments, acute kidney injuries drive up health care costs, as patients who suffer stage 1, 2 or 3 kidney injuries typically spend an extra 3.5 days in the ICU.

The rate of acute kidney injuries is so high, Chang says, because doctors can’t adequately identify the optimal blood pressure for individuals during surgery, a level that varies based on patient size, fitness, medical history and many other variables. The current gold standard of care in detecting AKI is observing a rise in serum creatinine, a blood biomarker, but this doesn’t happen until 24 to 48 hours after the injury has occurred.

“In cardiac surgery, doctors rely on generalized guidelines to set people’s blood pressure, but every person is different,” Chang says. “If these guidelines don’t fit the individual, the patient’s kidneys essentially hold their breath for the entire one- to three-hour procedure. There’s currently no way to see in real time how the kidneys are doing during surgery.”

Chang founded Renalert in 2015 to develop a real-time urine analysis device for the prevention of acute kidney injury. Currently operating out of Johns Hopkins Technology Ventures’ (JHTV) FastForward 1812 innovation hub, Renalert’s device sits beneath operating tables and monitors patient urine in real time, providing more precise measurements than the visual analyses typically used, while also incorporating additional correlations to other real-time vital signs.

A recent 30-patient pilot study Chang organized at Johns Hopkins Hospital showed observational significance between low urine flow during surgery and higher rates of acute kidney injuries.

“If doctors knew of potential injury earlier, there’s plenty of ways they could ensure the patient’s kidneys are perfused,” Chang says. “If at a certain blood pressure no urine is coming out, the doctor would know to increase it.”

With more studies currently underway at Johns Hopkins Hospital and Northwestern Memorial Hospital, Chang hopes to optimize the device’s algorithm and validate these results.

Chang has also begun discussions with Johns Hopkins’ Technology Innovation Center to allow Renalert’s device to feed information into EPIC, Johns Hopkins’ integrated medical record system, to uncover other potential areas where Renalert could improve outcomes. After initial analyses, Chang has identified orthopaedics, liver transplants and minimally invasive surgeries as potential areas to examine.

Renalert’s efforts have received support from the Wallace H. Coulter Foundation, TEDCO’s Maryland Innovation Initiative and the Johns Hopkins School of Medicine Dean’s Faculty Innovation Award.

Though his vision for Renalert is clear, navigating the startup landscape is challenging. That’s why he has sought the support of JHTV, which provides Baltimore-area startups with the resources they need to reach their potential.

In addition to FastForward 1812’s proximity to the hospital, the support Renalert received in licensing technology, setting up a corporation correctly and building relationships with potential investors has made Baltimore an attractive place for the startup.

“FastForward provides pro bono legal services, connections with investors and affordable space in a beautiful building on the Johns Hopkins medical campus,” Chang says.

Want to learn more about FastForward? Click here.

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