Category: Awards


Student Startup Wins More Than $30,000 from Rice Business…

Student Startup Wins More Than $30,000 from Rice Business Plan Competition

May 14, 2019

The following was originally published in The Hub.

A Johns Hopkins engineering team took home more than $30,000 in grants and prizes from the Rice Business Plan Competition after presenting their designs for a device that makes corneal transplant surgery easier.

Kali Barnes and Eric Chiang pictured with the Best Life Sciences Startup Prize from the Rice Business Plan Competition. (Courtesy of The Hub)

Treyetech was selected out of more than 300 applicants to compete in the life sciences/medical devices/digital health category. The company received four awards, including the TMCx Life Science Accelerator Prize, which was accompanied by an invitation to join the next cohort. The cash prizes included:

  • JLABS@TMC Best Life Science Startup Prize ($20,000)
  • Courageous Women Entrepreneur Investment Prize ($10,000)
  • Semifinal Round Flight 3, fourth place ($1,500)

Treyetech members Kali Barnes and Eric Chiang, who will graduate with their master’s degrees in biomedical engineering next week, presented the team’s work. Together with their Treyetech teammates, they have created a device that prepares and transports a donor’s cornea graft from an eye bank to surgeons, eliminating an unrolling step and allowing for a more effective and successful insertion into the eye.

Corneal transplants can be difficult due to the tissue’s propensity for scrolling up on itself, making it difficult to unroll during implantation. The Treyetech method uses a specific folding configuration and a proprietary device that allows the tissue to pop into place naturally once transplanted.

The company is pursuing patents for its technology through Johns Hopkins Technology Ventures. Its device is being used successfully in canine corneal transplantation in Washington and at the University of California, Davis.

Treyetech previously received grant funding from the Ralph S. O’Connor Undergraduate Entrepreneurship Fund through FastForward U.

Treyetech has also snagged victories at the Texas Christian University’s Values and Ventures Business Plan Competition in 2017 and received a Lemelson-MIT Student Prize in 2018, among other competitive wins.

The Rice Business Plan Competition is the world’s largest graduate-level student startup competition, designed to give college entrepreneurs an opportunity to fine-tune their business plans and elevator pitches. This year’s competition brought together 42 teams to compete for various grants and monetary prizes.


Inaugural Recipients Named for Bisciotti Foundation Translational Fund Grants

Inaugural Recipients Named for Bisciotti Foundation Translational Fund Grants

March 8, 2019

Four Johns Hopkins professors are the inaugural recipients of grants for their research through the Bisciotti Foundation Translational Fund.

Established with a generous multiyear gift from the Stephen and Renee Bisciotti Foundation, the fund provides $300,000 annually in seed money to advance Johns Hopkins discoveries on a commercial path. Recipients are awarded between $25,000 and $100,000 to conduct their work over a period of up to nine months.

For the inaugural funding round, 17 applications were submitted. Finalists presented their work in February to an outside panel of scientists, researchers and investors.

All of the applicants have made a report of invention to Johns Hopkins Technology Ventures.

“We were pleased with the diverse set of technologies represented among the applicants and awardees, from solar cells to surgical tools to cancer therapies,” says Nina Urban, associate director of FastForward, JHTV’s startup program. “This represents the breadth and depth of Hopkins innovation.”

The annual application deadline for the Bisciotti Translational Fund is Oct. 15. The deadline for applications for another translational fund, the Louis B. Thalheimer Fund for Translational Research, is March 15.

Susanna Thon

Diffuse-Light-Collecting Microconcentrators for High Efficiency Solar Cells

Principal investigator: Susanna Thon, assistant professor of electrical and computer engineering

The pitch: Making solar energy cheaper and more widely deployable with the next generation of solar cells.

There are two main ways to increase the power output of solar cells: Create new materials with excellent solar-cell properties or improve the device’s architecture to increase efficiency. Silicon-based solar cells now dominate the market, but they are energy-intensive to produce, and they require large amounts of material. Thon and her colleagues at the Whiting School of Engineering have developed and tested concentrators to maximize light absorption in third-generation solar cells in a cost-effective way. The technology dramatically increases power output by creating lenses that can be bonded directly to solar cells and deliver up to 20 times the current of existing third-generation technologies. The compact design allows the solar-cell-concentrator systems to be placed on any surface to collect diffuse light without tracking the sun, unlike traditional concentrator technology. Johns Hopkins Technology Ventures is pursuing patent protection for the technology.

Edward James Wright III

Mitigation of Implant Migration Risk in a Preclinical Model for Endoscopic Urethral Reconstruction

Principal investigator: Edward James Wright III, director, Division of Neurological and Reconstructive and Neurological Urology, and chief of urology at Johns Hopkins Bayview Medical Center

The pitch: A disposable medical device to repair a urethral stricture without invasive surgery.

More than $300 million is spent annually treating urethral strictures — scar tissue that narrows the urethra, resulting in restricted, painful and frequent urination. Current treatment options include urethrotomy, an internal incision to widen the stricture. This procedure is minimally invasive but marginally effective, and when repeated can worsen the scarring. Another current option is urethroplasty, an effective but invasive and complex reconstructive procedure that urologists rarely perform. Wright and a team of engineers created a disposable graft carrier and retrieval device that enters the urethra through its natural orifice, then expands to a precise size at the target site and adheres to the urethra. The device is retrieved seven to 10 days later, leaving the now integrated graft behind and resulting in a widened urethral caliber and improved flow. The procedure is done endoscopically and can be performed by a general urologist. JHTV is pursuing patent protection for the technology.

Warren Grayson

Structural and Mechanical Assessments of BiO2-Bone Scaffolds for Regenerating Craniofacial Bone

Principal investigator: Warren Grayson, associate professor, Department of Biomedical Engineering

The pitch: A novel way to repair large facial bone loss from cancer or congenital disorders.

The most reliable treatment of large bone defects in the face is to transplant bone from another part of the patient’s body. But the procedure is costly, can take more than 12 hours and often requires multiple revision surgeries. Grayson, who oversees a lab devoted to craniofacial and orthopaedic tissue engineering, wants to use the patient’s stem cells combined with scaffolds to regenerate bone tissue. The scaffolds are 3D-printed and contain oxygen-delivering “microtanks” that help the stem cells survive, proliferate, regenerate bone mineral tissue and form vascular networks. Grayson is setting up a company through JHTV’s FastForward program, and JHTV is pursuing patent protection related to the technology.

Tian-Li Wang

Development of Small Molecule Compounds Targeting PBX1/DNA Transcriptional Complex

Principal investigator: Tian-Li Wang, professor of pathology, oncology and gynecology/obstetrics

The pitch: A novel molecule that can treat chemotherapy-resistant ovarian cancer.

Approximately 22,000 women receive a new diagnosis of ovarian cancer each year, with an average five-year survival rate of 50 percent. While ovarian cancer is initially responsive to surgery and chemotherapy, more than 70 percent of patients experience a recurrence. Wang and colleagues have discovered a compound that targets a protein found at significantly high levels in recurrent ovarian cancer cases. Should the compound prove effective at inhibiting ovarian cancer, a future drug could be used to treat other recurrent diseases, including breast cancer. Wang’s team recently formed a company through FastForward and is considering licensing the technology. JHTV is pursuing patent protection for the technology.

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